Results of the Conservative Surgery for Laryngeal Cancer

نویسندگان

  • Felipe Guilherme da Silva Souza
  • José Luiz Ortiz
  • Rogério Aparecido Dedivitis
چکیده

Introduction: The techniques of partial laryngectomy are based on the compartimentalization of the larynx and their aims are to provide the oncologically radical excision and to preserve the laryngeal function. Objective: To evaluate the oncological results and the complications in patients submitted to these techniques. Methods: A consecutive series of 120 patients underwent partial laryngectomy from 1996 to 2016, according to the local clinical staging (T). The surgical margins were evaluated for frozen section examination during the surgery. The follow up varied from 4 to 120 months (median, 48.5). Adjuvant radiation therapy was indicated according to the lymph node staging (pN+). The following complications were evaluated: edema of the arytenoid, pharyngocutaneous or laryngocutaneous fistula, pneumonia, haemorrhage, dysphagia, wound infection, laryngeal stenosis and glottic insufficiency. Results: The free of disease survival was: 84.6% for T1 tumors; 84.5% for T2; and 40% for T3. After the surgical salvage, the ultimate survival was: 97% for T1; 92.9% for T2; and 40% for T3. There was edema of the arytenoid in 7 patients, laryngocutaneous fistula in 4; wound infection in 3; pneumonia in 5; dysphagia in 1; and laryngeal stenosis in 6. Conclusions: The global disease free survival rate after treatment was of 84,6% in T1, 84,5% in T2 and 40% in T3, with better results in earlier staged tumors. Complications incidence is acceptable and can be treated conservatively.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Assessment of Surgeon Judgment during Resection of Laryngeal Carcinoma

Carbon dioxide (CO2) laser surgery as a conservative tool plays a peculiar role in the management of head and neck cancer. Numerous patients who were candidates for transoral laryngeal microsurgery have forced us to eliminate frozen-section evaluation of surgical margins and use a magnified view of the larynx. The present study evaluated surgeon-judged negative margins with permanent microscopi...

متن کامل

بررسی تغییرات کلینیکی و آزمایشگاهی تیروئید پس از لارنژکتومی توتال در کانسر حنجره

Background: Hypothyroidism is a well-documented complication after treatment of laryngeal cancer and is particularly significant among patients undergoing laryngectomy. We investigated the frequency of hypothyroidism in patients treated with total laryngectomy for laryngeal cancer. We also evaluated the effect of neck radiotherapy on thyroid function after total laryngectomy for laryngeal cance...

متن کامل

Assessment of nutritional parameter outcome in laryngeal cancer patients undergoing laryngectomy

Introduction: Laryngectomy in patients with laryngeal cancer can lead to the reduction of nutritional parameters. Supportive treatments and supplementary nutritional supports are recommended in all patients undergoing laryngectomy, even with acceptable preoperative nutritional indices.The aim of this study was to evaluate postoperative changes in nutritional parameters in patients with larynge...

متن کامل

The Study of Vocal Function in Patients With Early Laryngeal Carcinoma After Transoral Laser Microsurgery

Objective Today transoral laser microsurgery is considered as one of the first options to control early laryngeal cancer, and voice disorder is one of the inevitable complications of this therapeutic component. This study aimed to compare the vocal function in patients with early-stage laryngeal cancer following laser surgery with healthy individuals with normal voice quality using acoustic ana...

متن کامل

Relationship of Podoplanin and Glutathione S-transferases T1 Expression with Laryngeal Cancer

The aim of this study is to determine whether there is a role of podoplanin and glutathione S-transferases T1 (GST-T1) expression in laryngeal squamous cell carcinoma. The study was completed with 33 patients and gene expression analysis was performed by qRT–PCR. The podoplanin and GST-T1 expression patterns were analyzed to determine their correlation with clinicopathologic parameters of lar...

متن کامل

P-173: Conservative Treatment in Young Patients with Cervical Cancer: A Review

Background: Fertility preservation in young patients with cervical cancer is a novel point which considers these days and in Iran we have a new experiment that was successful. Materials and Methods: Evaluation of literature review and our experiences in conservative management in patients with early stage cervical cancer. The key words in this research were conservative management, young women ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017